Marcadores bioquímicos en el diagnóstico de síndrome metabólico en la población adulta. Una revisión sistemática según las directrices PRISMA

Abstract

Introduction: Biochemical markers are a potential tool; their role is to indicate early alterations in biological processes (1). Metabolic syndrome (MetS) increases the risk of cardiometabolic diseases. Therefore, it is important to establish an early and accurate diagnosis (2,3). The purpose of this study is to investigate the potential of biochemical markers as a diagnostic method for MetS. Objective: To synthesize the scientific evidence on biochemical markers in the diagnosis of metabolic syndrome in the adult population. Method: Integrative, observational, retrospective study of Systematic Review of Literature in the adult population, according to the guidelines PRISMA. For the search of the information, the databases of electronic literature were used: SCOPUS, ScienceDirect, EBSCO and PubMed. The collection instrument is a data extraction matrix elaborated in Microsoft Excel 2019 that contains the relevant information for the preparation of the study. The quality assessment was carried out using the Sackett scale (Annex 1). For the control of biases, the ROBINS tools (Annex 2) were used. The quantitative approach used descriptive statistics and the qualitative approach the contrast in narrative form of the information obtained. Results: 15 articles were analyzed, most of them made in Asian countries and it was determined that the biochemical markers used in the diagnosis of MetS are: serum adiponectin, superoxide dismutase and serum resistin. Conclusion: The biochemical markers have the ability to identify the development of MetS regardless of the conventional criteria established by IDF and NCEP-ATPIII.