Prevalencia y factores asociados a respuesta completa a la primera línea de quimioterapia en pacientes con diagnóstico de linfoma difuso de células b, en el Instituto del Cáncer Solca Cuenca-Ecuador

Abstract

Lymphomas are a heterogeneous group of lymphoproliferative disorders that are classified according to their histology, of which B-cell lymphomas represent 80% of all lymphomas. Diffuse large B-cell lymphoma (DLCGB) is the most frequent form of lymphoma, representing 30-35% of the total. Several cytotoxic therapies have been developed, which seek a better therapeutic response with the lowest degree of adverse events, the first-line chemotherapy is RCHOP with an adequate response. The factors associated with the response to first-line treatment are stage, age, general condition, LDH levels, tumor burden.