Eje hipotalámico hipofisario suprarrenal y su influencia en los trastornos temporomandibulares

Abstract

Objective: to review the literature to understand the mechanism of action of the hypothalamic-pituitary-adrenal axis in cortisol production and its influence on temporomandibular disorders. Materials and Methods: a literature search was performed, in English and Spanish languages, in Pubmed platforms, as well as books using the following keywords. Cor-tisol, Temporomandibular disorders, Stress, Hypothalamic-pituitary-adrenal axis. Conclusions: Depression, anxiety, lack of sleep and pain are considered disorders with a negative impact on the emotional, social and general well-being of individuals, activating physiological stress systems and triggering detrimental health effects. Stress is related to the etiopathogenesis of TMDs, the HPA axis is activated upon perception of a stressor by releasing cortisol.