Prevalencia de lesiones óseas metastásicas diagnosticadas mediante gammagrafía MDP en pacientes con cáncer de próstata en el Instituto del Cáncer Solca, Cuenca 2020 - 2021

Abstract

Background: Bone metastases in patients with prostate cancer result from tumor dissemination that has spread to the bone from its original location. (1) Bone scintigraphy is often the diagnostic imaging technique when bone metastases are suspected because it is a functional test that allows to assess the appearance of bone metabolism. (2) Objective: To determine the prevalence of metastatic bone lesions diagnosed by MDP Scintigraphy in patients with prostate cancer at SOLCA Cancer Institute, Cuenca 2020-2021. Methodology: The study was descriptive, retrospective, and cross-sectional. The database provided by SOLCA Cancer Institute, Cuenca, was analyzed by applying study variables through data collection forms and digital processing using IBM SPSS v26. Results: 268 medical records of patients with prostate cancer were analyzed; metastatic bone lesions were found in 91 patients (34%). The age range with the highest prevalence was 73-83 years (47.3%); the most frequent number of injuries was higher than 7 (42.9%): the spine was the most common location of involvement (21.6%). The total prostate-specific antigen (PSAt) level was >20 ng/mL in 69 patients (75.8%) and the most frequent Gleason score was 8-10 (81.3%). Conclusions: Metastatic bone lesions are more frequent in patients in the age range of 73-83 years. According to the number of lesions, the existence of more than 7 is more frequent and the most affected location is the spine.