Características clínicas y epidemiológicas de la amiloidosis sistémica en el Instituto del Cáncer SOLCA-Cuenca. 2005-2021

Abstract

Background: Systemic amyloidosis and its types have a diverse clinical presentation which becomes a great challenge for the clinician, therefore, it is important to describe information on the clinical manifestations and epidemiological data of our reality. Objective: To describe the clinical and epidemiological characteristics of systemic amyloidosis at the SOLCA Cancer Institute, Cuenca 2005-2021. Methodology: A descriptive quantitative research was carried out; the universe consisted of 10 patients diagnosed with systemic amyloidosis at the SOLCA Cancer Institute in Cuenca, during the period 2005-2021; the data were obtained from clinical records and were analyzed by means of frequency, tables with the statistical calculation program Microsoft Excel 2021, and the statistical package Epi Info 7. Results: The most affected organ in the population studied was the kidney; 90 % of the patients had organ-specific clinical characteristics and an oncologic pathology as the basis. The 60 % received chemotherapy as therapeutic management, 50 % did not have a survival greater than one year of disease, 70 % relapsed and died. Conclusions: The kidney was the most affected organ, most showed organ-specific characteristics and had a history of oncologic pathology. Chemotherapy was the main treatment, half of the studied population did not reach one year of survival, all patients who relapsed, died.