Marcador Ca-125, en tumores epiteliales malignos de ovario y factores asociados, en pacientes del Instituto del Cáncer SOLCA, Cuenca 1996 - 2016

Abstract

INTRODUCTION: Ovarian cancer is a leading cause of death in the world, its diagnosis is late, it is a silent killer and a dismal prognosis. Treatment is based on staging. Currently used The Ca-125 for detection, and as a prognostic-follow-up factor. Normal levels are at 35IU/ml; Because of its low sensitivity and specificity, is used with other diagnostic methods such as imaging

OBJECTIVE: To determine levels of Ca-125 marker in malignant epithelial ovarian tumors and associated factors in patients from the Cancer Institute SOLCA, Cuenca 1996 - 2016

METHODOLOGY: An observational cross-sectional prevalence study, carried out at SOLCA between 1996 and 2016. Data processed SPSS Statics v15.0.

RESULTS: Mean age of 53 years (DS 15.12), 25.50% with a family history of cancer, 75.17% presented parity, of which 4.46% used hormone replacement therapy, the serous epithelial type (81.21%) was the predominant, the most frequent tumor stage was III (32.89%), Ca-125 was positive in 86.58% of the cases.

CONCLUSIONS: The prevalence is 1.6 per 1.000 women attended at the consultation, the age of the population was 53 years and a married civil status, concordances were found with other studies regarding the elevation of Ca-125, stages and histological subtypes of cancer