Anormalidades cromosómicas, mediante citogenética convencional en abortos espontáneos, en pacientes del Hospital Vicente Corral Moscoso. Cuenca. 2016

Abstract

BACKGROUND: The human reproduction is considered as a relatively inefficient process; the spontaneous abortions occur in 10-15% of all clinically recognized pregnancies. Chromosomal abnormalities are one of the main causes for such loss occurs. To this postponement of motherhood which directly influences a high incidence of chromosomal abnormalities adds. In addition, statistics of chromosomal aberrations in spontaneous abortions amounted to gestational age and if the woman has a history of abortions. (1) (2) OBJECTIVE: To determine by conventional cytogenetics chromosomal abnormalities in spontaneous abortions in patients Hospital Vicente Corral Moscoso in 2016. METHODS: An observational, analytical cross-sectional study was conducted in a six-month period 100 samples were collected abortion. As laboratory method analysis abortion tissues used by conventional cytogenetics; plus the patient data were obtained through a form, they were tabulated and associated with the result of the karyotype. The data obtained were analyzed in the SPSS version 1.8 software in Spanish and Excel 2010. RESULTS AND CONCLUSIONS: We obtained 59 karyotypes of processed samples and 33.9% had chromosomal abnormalities, the most common abnormalities were aneuploidy by 50%. No statistically significant association with the associated variables found. The results of the study were provided to each of the patients it was useful for counseling